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This treatment applies to the following species:
(eprinomectin)
Extended-Release Injectable Parasiticide
5% Sterile Solution
For the Treatment and Control of Internal and External Parasites of Cattle on Pasture with Persistent Effectiveness
Not for use in female dairy cattle 20 months of age or older, including dry dairy cows. Not for use in calves to be processed for veal.
Not for use in breeding bulls, or in calves less than 3 months of age.
Not for use in cattle managed in feedlots or under intensive rotational grazing.
What is LongRange Extended-Release Injectable Parasiticide
LONGRANGE® (eprinomectin) is a ready-to-use, sterile injectable preparation containing eprinomectin, a member of the macrocyclic lactone class of antiparasitics. Each mL of LONGRANGE contains 50 mg of eprinomectin in a co-solvent system of N-methyl-2-pyrrolidone (30% v/v) and triacetin (qs), along with 50 mg of poly-lactide-co-glycolic-acid 75:25 (PLGA), a polymer that allows a slow release of eprinomectin from the formulation, thereby maintaining a prolonged duration of product effectiveness. Butylated hydroxytoluene (0.2 mg/mL) acts as an antioxidant in the formulation.
LONGRANGE Indications For Use
BUY LONGRANGE, when administered at the recommended dose volume of 1 mL per 110 lb (50 kg) body weight, is effective in the treatment and control of the following internal and external parasites of cattle:
| Gastrointestinal Roundworms | Lungworms |
| Bunostomum phlebotomum – Adults and L4 | Dictyocaulus viviparus – Adults |
| Cooperia oncophora – Adults and L4 | |
| Cooperia punctata – Adults and L4 | |
| Cooperia surnabada – Adults and L4 | Grubs |
| Haemonchus placei – Adults | Hypoderma bovis |
| Oesophagostomum radiatum – Adults | |
| Ostertagia lyrata – Adults | Mites |
| Ostertagia ostertagi – Adults, L4, and inhibited L4 | Sarcoptes scabiei var. bovis |
| Trichostrongylus axei – Adults and L4 | |
| Trichostrongylus colubriformis – Adults |
Persistent Activity
LONGRANGE has been proven to effectively protect cattle from reinfection with the following parasites for the indicated amounts of time following treatment:
| Parasites | Durations of Persistent Effectiveness |
| Gastrointestinal Roundworms | |
| Bunostomum phlebotomum | 150 days |
| Cooperia oncophora | 100 days |
| Cooperia punctata | 100 days |
| Haemonchus placei | 120 days |
| Oesophagostomum radiatum | 120 days |
| Ostertagia lyrata | 120 days |
| Ostertagia ostertagi | 120 days |
| Trichostrongylus axei | 100 days |
| Lungworms | |
| Dictyocaulus viviparus | 150 days |
LONGRANGE Dosage And Administration
LONGRANGE® (eprinomectin) should be given only by subcutaneous injection in front of the shoulder at the recommended dosage level of 1 mg eprinomectin per kg body weight (1 mL per 110 lb body weight).
Each mL of LONGRANGE contains 50 mg of eprinomectin, sufficient to treat 110 lb (50 kg) body weight. Divide doses greater than 10 mL between two injection sites to reduce occasional discomfort or site reaction.
| Body Weight (lb) | Dose Volume (mL) |
| 110 | 1 |
| 220 | 2 |
| 330 | 3 |
| 440 | 4 |
| 550 | 5 |
| 660 | 6 |
| 770 | 7 |
| 880 | 8 |
| 990 | 9 |
| 1100 | 10 |
BUY LONGRANGE is to be given subcutaneously only. Animals should be appropriately restrained to achieve the proper route of administration. Inject under the loose skin in front of the shoulder (see illustration) using a 16 or 18 gauge, 1/2 to 3/4 inch needle.
Sanitize the injection site by applying a suitable disinfectant. Clean, properly disinfected needles should be used to reduce the potential for injection site infections.
50 mL bottle size: Use only polypropylene syringes. Not for use with polycarbonate syringe material. If syringe material is not known, contact the syringe manufacturer prior to use for identification. Alternatively, a 50-mL polypropylene repeater syringe compatible with LONGRANGE may be used. To obtain a list of compatible equipment. Do not use beyond 3 months after stopper has been punctured. Discard bottle after 15 stopper punctures. LONGRANGE should not be stored in the repeater syringe.
250 mL and 500 mL bottle sizes: Use only automatic syringe equipment provided by Merial. To obtain compatible equipment, contact your veterinarian. LONGRANGE should not be stored in automatic syringe equipment. Automatic syringe equipment should be thoroughly cleaned after each use. Discard bottle after one stopper puncture with draw-off spike.
Alternatively, a 50-mL polypropylene repeater syringe compatible with LONGRANGE may be used. To obtain a list of compatible equipment. When using a repeater syringe, do not use beyond 3 months after stopper has been punctured. Discard bottle after 15 punctures. LONGRANGE should not be stored in the repeater syringe.
No special handling or protective clothing is necessary.
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