Zoletil™ for Injection (tiletamine and zolazepam for injection) is a nonnarcotic, nonbarbiturate, injectable anesthetic agent for dogs and cats. Chemically, Zoletil™ for Injection is a combination of equal parts by weight of base of tiletamine hydrochloride (2-[ethylamino]-2-[2-thienyl]-cyclohexanone hydrochloride), an arylaminocycloalkanone dissociative anesthetic, and zolazepam hydrochloride (4-[o-fluorophenyl]-6, 8-dihydro-1,3,8- trimethylpyrazolo [3, 4-e] [1,4] diazepin-7 [1H]-1- hydrochloride), a non-phenothiazine diazepinone having minor tranquilizing properties. The product is supplied sterile in vials. The addition of 5 mL diluent produces a solution containing the equivalent of 50 mg tiletamine base, 50 mg zolazepam base and 57.7 mg mannitol per milliliter. This solution has a pH of 2 to 3.5 and is recommended for deep intramuscular injection.
2 MOLECULES, 1 INJECTION
2-in-1 combined anesthesia. Dogs – for restraint and minor procedures. Cats – for restraint and anesthesia combined with muscle relaxation.
Zoletil™ for Injection delivers:
- Rapid onset of action
- Wide therapeutic window
A combination of 2 complementary molecules in an optimized formulation:
- Tiletamine – a dissociative agent that produces the following effects: anesthesia and analgesia.
- Zolazepam – a benzodiazepine molecule that produces the following effects: tranquilization and muscle relaxation.
Dosage
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