Rispoval Pasteurella 25d use For active immunisation of cattle to reduce lesions and respiratory disease caused by Pasteurella haemolytica biotype A, serotype 1.Studies carried out show that a single dose is sufficient to confer protection from challenge by Pasteurella haemolytica within 7 days of vaccination.The vaccine will protect animals for at least 17 weeks.
Inactivated, adjuvanted Pasteurella haemolytica vaccine. An off-white freeze-dried pellet containing antigens of Pasteurella haemolytica biotype A, serotype 1, strain NL 1009:
Leukotoxoid 380 – 1276 RU*
Capsular antigens 565 – 10208 RU*
Supplied together with a vial of emulsion containing aluminium hydroxide and liquid paraffin as adjuvant. (* ELISA relative units per dose).
For the active immunisation of cattle to reduce lesions and respiratory disease caused by Pasteurella haemolytica biotype A, serotype 1.
Studies carried out show that a single dose is sufficient to confer protection from challenge by Pasteurella haemolytica within 7 days of vaccination. The vaccine will protect animals for at least 17 weeks.
Reconstitute the vaccine by first shaking the vial containing the emulsion, and then aseptically withdraw and add all of the emulsion to the vial containing the lyophilisate. Shake well and aseptically administer 2 ml intramuscularly.
Do not use chemically sterilised syringes or needles.
A single two ml dose of reconstituted vaccine to be given to healthy cattle over the age of 3 months.
A single dose of vaccine will protect animals for at least 17 weeks. Should cattle be at risk from pasteurellosis at a subsequent time, a single vaccination is recommended at least 7 days prior to the period of expected disease challenge.
Calves should be vaccinated at least 7 days before transport, mixing of animals of different origins, housing or any other event which may cause the animals to be stressed or exposed to new infections. Calves are usually most susceptible during early autumn.
Do not vaccinate unhealthy animals, pregnant animals or heifers at the time of breeding.
Very rarely, hypersensitivity reactions may occur. In such cases, appropriate treatment (eg adrenaline and/or antihistamine) should be given without delay.
A mild, transient fever might be observed 24 to 48 hours after vaccination in some animals. Temperatures return to normal in the following 24 to 48 hours without remedial action.
A mild, transient local swelling might be observed at the site of injection 24 to 48 hours after vaccination in a small number of animals. These swellings do not generally cause discomfort to the animals even on palpation. The average size of reaction 48 hours after vaccination was 5 cm in diameter, reducing to half that size by day 5. In the majority of cases site reactions are undetectable by 14 days after vaccination but occasionally might be observed for up to 48 days.
Short-term discomfort around the injection site and muscular trembling have been noted very rarely.
Ensure that the method of restraint, handling and administration, eg by the use of guarded needles, minimizes the risk of accidental injection/self-injection.
To the user
This product contains mineral oil. Accidental injection/self-injection may result in severe pain and swelling, particularly if injected into a joint or finger, and in rare cases could result in the loss of the affected finger if prompt medical attention is not given.
If you are accidentally injected with this product, seek prompt medical advice even if only a very small amount is injected and take the package leaflet with you. If pain persists for more than 12 hours after medical examination, seek further medical advice.
To the doctor
This product contains mineral oil. Even if small amounts have been injected, accidental injection with this product can cause intense swelling which may, for example, result in ischaemic necrosis and even the loss of a digit . Expert, PROMPT, surgical attention is required and may necessitate early incision and irrigation of the injected area, especially where there is involvement of finger pulp or tendon.
Rispoval Pasteurella 25d Withdrawal period